Stem Cells & Orthobiologics

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Treating your Orthopedic Conditions with Orthobiologics & Stem Cells

Orthobiologics are substances harvested from a patients’ blood or bone marrow. They have growth factors and in some cases stem cells that are used to enhance the body’s ability to heal more quickly. Platelet rich plasma (PRP) is commonly being used to treat many different musculoskeletal conditions including arthritis, muscles strains, tendon and ligament injuries. Similarly, bone marrow aspirate concentration (BMAC) is being used as well with the potential additional upside of containing mesenchymal stem cells (MSCs). Additionally, both have been used as augmentation for surgical cases.

How can Orthobiologics help me?

Orthobiologics have been employed to help either with pain relief or healing of orthopedic ailments. Generally, its use can be grouped into one of four categories of orthopedic injuries: chronic tendon injuries (i.e. tennis elbow), acute soft tissue injuries (hamstring strains/tears), arthritis, and surgical augmentation. Some conditions have promising results published in the orthopedic literature such as tennis elbow (lateral epicondylitis) and knee osteoarthritis.  Other conditions such as fractures, rotator cuff tears, patellar tendonitis, Achilles tendonitis, plantar fasciitis, muscular strains/tears, shoulder osteoarthritis, hip osteoarthritis, and many other conditions have been less rigorously tested with mixed results.  It is important to remember that these procedures have been deemed safe, however even though our understanding of orthobiologics role is expanding, it is still largely unproven.  There are many scenarios where orthobiologics will not work, thus the treatment strategy will be used judiciously.

What is involved in the procedure?

All doctors at DMOS will have the ability to discuss orthobiologics with a patient and recommend them for an injection only after a thorough history and physical has been completed. The patient will then be enrolled in one of our weekly clinics to administer the treatment.  As Orthopedists, we pride ourselves on having a unique expertise that combines unparalleled knowledge of musculoskeletal anatomy, with a vast amount of clinical insight.  Every patient treated by our physicians will receive an image guided injection, using either an ultrasound or fluoroscopy to ensure accurate delivery of the injection to the injured tissue. Our recommended patient follow-up will consist of multiple clinic visits to assess the patient for progress – and ultimately complete recovery. Often times a tailored physical therapy regimen, or bracing, may accompany the patient to aid in their recovery.

Orthobiologics Available

We offer three types of injections, all commonly used to treat many different musculoskeletal conditions including arthritis, muscles strains, tendon and ligament injuries. The injection type differs based on the patient assessment and their individualized needs.

  • Platelet Rich Plasma (PRP) – By definition, PRP is a collection of growth factors (which are proteins that are important in the healing of injuries), that can have controlled levels of white and red blood cells, based on the healing process necessary. Laboratory studies have shown that the increased concentration of growth factors in PRP can potentially speed up the healing process.
  • Bone Marrow Aspirate Concentrate (BMAC) – Technically, BMAC is a collection of growth factors and cells, which include stem cells. BMAC is used when the physician believes that the potential additional upside of containing mesenchymal stem cells (MSCs) is required for treatment.
  • Autologous Protein Solution (APS) – In technical terms, APS is a denatured PRP that delivers proteins, which block arthritic pain receptors. APS may be the preferred course of treatment based on if the patient exhibits radiographic evidence of knee OA (osteoarthritis).

Physicians Offering Orthobiologics & Stem Cell Injections

Patrick Sullivan, M.D.

Patrick Sullivan, M.D.

Hip, Knee & Shoulder Surgeon

Dr. Sullivan's practice focuses on hip, knee and shoulder replacement surgeries.
Primary Location: DMOS West, 6001 Westown Parkway, West Des Moines, IA 50266
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Ian Lin, M.D.

Ian Lin, M.D.

General Orthopaedics; Sports Medicine, Hip & Knee Replacements

Dr. Lin's practice encompasses most area of general orthopedics, including special interests in joint replacement, arthroscopy and sports medicine as well as trauma care.
Primary Location: DMOS East, 1301 Penn Ave., Suite 213, Des Moines, Iowa 50316
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Physician Assistant/s:
Shawna Swain, P.A.-C.

Mark Isaacson, D.O.

Mark Isaacson, D.O.

Joint Replacement and General Orthopaedics

Dr. Isaacson specializes in total knee and hip arthroplasty, complex revision knee and hip arthroplasty, minimally invasive direct anterior hip replacement, knee and shoulder arthroscopy, adult and pediatric fracture care, partial knee arthroplasty, sports-related injury management, as well as workers compensation injuries and some conditions of the hand and wrist.
Primary Location: DMOS Ankeny, 350 NE 36th Street, Ankeny, IA 50021
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Nicholas Honkamp, M.D.

Nicholas Honkamp, M.D.

Sports Medicine, Knee & Shoulder Surgeon

Dr. Honkamp's orthopaedic practice specializes in all aspects of shoulder and knee injuries from arthroscopic treatments to joint replacement.

Primary Location: DMOS West, 6001 Westown Parkway, West Des Moines, IA 50266
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Jon Gehrke, M.D.

Jon Gehrke, M.D.

General Orthopaedics

Dr. Gehrke has built his practice with the emphasis in general orthopaedics, and special expertise in orthopaedic foot and ankle surgery.
Primary Location: DMOS West, 6001 Westown Parkway, West Des Moines, IA 50266
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