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Mark Isaacson, DO

Mark Isaacson headshot

Mark Isaacson, DO

Hip & Knee Surgeon

Iowa native Dr. Mark Isaacson completed his medical degree at Des Moines University in 2009. After medical school, he completed an orthopedic internship and residency at Ohio University in Columbus, Ohio. Dr. Isaacson completed fellowship training in adult reconstruction at the Houston Methodist Hospital at Texas Medical Center.

He is committed to working with his patients so that they fully understand their injury or condition and feel confident that their treatment plan is right for them.

Outside of seeing patients, Dr. Isaacson enjoys living an active lifestyle. He enjoys running, playing golf, and outdoor activities as well as being involved in a variety of community school and church programs in the Ankeny area. Above all, Dr. Isaacson enjoys spending time with his family.

  • Ankeny · 350 NE 36th Street, Ankeny, IA 50021
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Medical Education
  • Des Moines University
    Des Moines, IA
Fellowship Training
  • Adult Reconstruction, Houston Methodist Hospital at Texas Medical Center
    Houston, TX
Board Certified
  • American Board of Orthopaedic Surgery
Orthopaedic Residency
  • Ohio University
    Columbus, OH
  • American Academy of Orthopaedic Surgeons
  • American Association of Hip & Knee Surgeons
  • American Osteopathic Academy of Orthopedics
  • American Osteopathic Association


  • Same-day joint replacement
  • Direct anterior hip replacement
  • Robotic-Assisted Mako partial knee replacement
  • Regenerative Medicine – Platelet-Rich Plasma (PRP), Bone Marrow Aspirate Concentrate (BMAC), Autologous Protein Solution (APS)
  • Arthroscopic knee and shoulder surgery
  • Pediatric fracture care
  • Sports-related injury care and management
  • Worker’s compensation injury

Dr. Isaacson's Team

Amy Lortz headshot

Amy Lortz, PA-C

Physician Assistant to: Dr. Mark Isaacson

Amy believes it is important to advocate for her patients, and hopes to give them a better understanding of their overall health and options to live the best life possible.

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Doctor Interviews & Insights

Dr. Isaacson talks Arthritis
Dr. Isaacson talks Partial Knee Replacement
Meet Dr. Mark Isaacson
Joint Effort: Computer Navigation and the use of Robotics during Surgery

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Dr. Isaacson's Reviews

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